Can Alternatives Inform the Risk Assessments of Mixtures in Food?
March 27, 2018
8:30 am-12:50 pm ET (GMT-4)
Wiley Auditorium, US FDA, College Park, Maryland
Chair: A. Wallace Hayes, University of South Florida College of Public Health, Tampa, FL, and Institute for Integrative Toxicology, Michigan State University, East Lansing, MI
Co-chair: Suzanne Compton Fitzpatrick, US FDA, College Park, MD
Registration for On-site Participation Deadline: March 19, 2018
Registration for Webcast
Colloquium website
SOT and the US FDA Center for Food Safety and Applied Nutrition (CFSAN) cordially invite you to join us for our March colloquium, “Can Alternatives Inform the Risk Assessments of Mixtures in Food?” Current risk assessments of chemicals in food do not generally consider exposure to multiple substances but rely instead on the assessment of individual substances in individual food commodities. Humans however are routinely exposed simultaneously to numerous chemicals in food. These mixtures can be variable and constantly changing and defining them presents a challenge. Models could be used independently and in an integrated manner to assess health impacts. This symposium will examine whether new testing approaches such as in vitro, in silico models, and non-mammalian in vivo models could be used to assess the potential health impacts of exposure to chemical mixtures in food.
Presentations include:
| 8:30 AM–8:35 AM | US FDA Welcome and Overview, Conrad J. Choiniere, Director, Office of Analytics and Outreach, CFSAN, US FDA, College Park, MD |
| 8:35 AM– 8:45 AM | Welcome from SOT and Introductions, Suzanne Fitzpatrick, CFSAN, USFDA, College Park, MD |
| Speaker Introductions, A. Wallace Hayes, Colloquium Chair, University of South Florida College of Public Health, Tampa, FL, and Institute for Integrative Toxicology, Michigan State University,East Lansing, MI | |
| 8:45 AM– 8:50 AM | Why a New Approach is Needed, A. Wallace Hayes, University of South Florida College of Public Health, Tampa, FL, and Institute for Integrative Toxicology, Michigan State University, East Lansing, MI |
| 8:50 AM– 9:30 AM | Can High Thru-put Assays/Tox 21 Inform the Risk Assessment? Michael J. Devito, NTP, Research Triangle Park, NC |
| 9:30 AM– 10:10 AM | Proposed In Silico Approach for Botanical Mixtures Catherine Mahoney, Procter & Gamble Technical Centres Ltd, Surrey, UK |
| 10:30 AM–11:10 AM | Non-Mammalian In Vivo Models: C. elegans as a Model System to Inform Hazard Identification Piper Reid Hunt, US FDA, Laurel, MD |
| 11:10 AM–11:50 AM | Extrapolating New Approaches into a Tiered Approach to Mixtures Risk Assessment Mike Dourson, Toxicology Excellence for Risk Assessment, Cincinnati, OH |
| 11:50 AM–12:50 PM | Roundtable Discussion Moderator: A. Wallace Hayes All speakers |